Evaluation of Pre-emptive Analgesia in Total Knee Arthroplasty During Early Post-operative Periods

Introduction: Pre-emptive analgesia is expected to decrease post-operative pain. The degree of soft tissue release directly related preoperative deformity; we presume the severity pain has a similar correlation in patients undergoing total knee arthroplasty (TKA). main purpose this research was evaluate effects pre-emptive different drugs TKA with degrees genu varus. Methods: In prospective observational study, 67 were enrolled varus deformity. They subdivided into two groups: those ≥15° and <15° deformities knee. Etoricoxib 60 mg pregabalin 75 administered orally all as hours before surgery. Parameters such amount release, visual analog score (VAS), range motion, complications, etc. documented from pre-operative period 72 post-TKA. Results: With post-TKA patients, VAS demonstrated statistically significant difference at 24, 48, hours. comparison intraoperative flexion between showed patients. Conclusion: use etoricoxib mg, surgery reduced scores correlated parameters associated medial for